Physical mapping of the CXC chemokine locus on human chromosome 4

@article{ODonovan1999PhysicalMO,
  title={Physical mapping of the CXC chemokine locus on human chromosome 4},
  author={N. O’Donovan and M. Galvin and John G. Morgan},
  journal={Cytogenetic and Genome Research},
  year={1999},
  volume={84},
  pages={39 - 42}
}
A physical map of the CXC chemokine locus on chromosome 4 has been constructed by PCR analysis and PFGE mapping of YAC clones. The genes for IL8, GRO1, PPBP, PF4, SCYB5 (ENA-78) and SCYB6 (GCP-2) have been co-localized on a 335-kb genomic fragment. The GRO2 and GRO3 genes did not map within this region and based on analysis of a YAC contig overlapping IL8 we speculate that GRO2 and GRO3 map downstream of this region. We have also assigned the novel CXC chemokine gene, SCYB9B (alias H174/βR1) to… Expand
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