Physical mapping in large genomes: accelerating anchoring of BAC contigs to genetic maps through in silico analysis

@article{Paux2007PhysicalMI,
  title={Physical mapping in large genomes: accelerating anchoring of BAC contigs to genetic maps through in silico analysis},
  author={Etienne Paux and Fabrice Legeai and Nicolas Guilhot and Anne-Françoise Adam-Blondon and Micha{\"e}l Alaux and J{\'e}r{\^o}me Salse and Pierre Sourdille and Philippe Leroy and Catherine Feuillet},
  journal={Functional & Integrative Genomics},
  year={2007},
  volume={8},
  pages={29-32}
}
Anchored physical maps represent essential frameworks for map-based cloning, comparative genomics studies, and genome sequencing projects. High throughput anchoring can be achieved by polymerase chain reaction (PCR) screening of bacterial artificial chromosome (BAC) library pools with molecular markers. However, for large genomes such as wheat, the development of high dimension pools and the number of reactions that need to be performed can be extremely large making the screening laborious and… CONTINUE READING
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