Physical map of the mouse λ light chain and related loci

@article{GerdesPhysicalMO,
  title={Physical map of the mouse λ light chain and related loci},
  author={Tobias Gerdes and Matthias R. Wabl},
  journal={Immunogenetics},
  volume={54},
  pages={62-65}
}
The λ light chain genes and the related loci λ5, V preB 1 and V preB 2 are selectively expressed in the development of B lymphocytes. The sequences and the order of the gene segments are known, but a precise physical map of the λ locus has not yet been published. Using the Celera mouse genome database we constructed such a map. In this paper, we confirm the order of the gene segments as being V λ 2 - V λ X - J λ 2 - C λ 2 - J λ 4 - C λ 4 - V λ 1 - J λ 3 - C λ 3 - J λ 1 - C λ 1 and give precise… CONTINUE READING