Physical limits of flow sensing in the left-right organizer

@inproceedings{Ferreira2017PhysicalLO,
  title={Physical limits of flow sensing in the left-right organizer},
  author={Rita R Ferreira and Andrej Vilfan and Frank J{\"u}licher and Willy Supatto and Julien Vermot},
  booktitle={eLife},
  year={2017}
}
Fluid flows generated by motile cilia are guiding the establishment of the left-right asymmetry of the body in the vertebrate left-right organizer. Competing hypotheses have been proposed: the direction of flow is sensed either through mechanosensation, or via the detection of chemical signals transported in the flow. We investigated the physical limits of flow detection to clarify which mechanisms could be reliably used for symmetry breaking. We integrated parameters describing cilia… CONTINUE READING
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