Physical interaction of two cancer-testis antigens, MAGE-C1 (CT7) and NY-ESO-1 (CT6).

@article{Cho2006PhysicalIO,
  title={Physical interaction of two cancer-testis antigens, MAGE-C1 (CT7) and NY-ESO-1 (CT6).},
  author={Hearn Jay Cho and Otavia L. Caballero and Sacha Gnjatic and Val{\'e}ria Cristina C. Andrade and Gisele W.B. Colleoni and Andre L Vettore and Hasina Hamilton Outtz and Sheila R Fortunato and Nasser Khaled Altorki and Cathy A Ferrera and Ramon Chua and Achim A. Jungbluth and Yao-Tseng Chen and L. John Old and Andrew J. G. Simpson},
  journal={Cancer immunity},
  year={2006},
  volume={6},
  pages={
          12
        }
}
Cancer/testis (CT) antigens are the protein products of germ line-associated genes that are activated in a wide variety of tumors and can elicit autologous cellular and humoral immune responses. CT antigens can be divided between those that are encoded on the X chromosome (CT-X antigens) and those that are not (non-X CT antigens). Among the CT-X antigens, the melanoma antigen gene (MAGE) family, defined by a shared MAGE homology domain (MHD), is the largest. CT-X genes are frequently expressed… CONTINUE READING
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