Physical crosslinking of collagen fibers: comparison of ultraviolet irradiation and dehydrothermal treatment.

@article{Weadock1995PhysicalCO,
  title={Physical crosslinking of collagen fibers: comparison of ultraviolet irradiation and dehydrothermal treatment.},
  author={Kevin S Weadock and Edward J. Miller and L D Bellincampi and J P Zawadsky and Michael G. Dunn},
  journal={Journal of biomedical materials research},
  year={1995},
  volume={29 11},
  pages={1373-9}
}
The strength, resorption rate, and biocompatibility of collagenous biomaterials are profoundly influenced by the method and extent of crosslinking. We compared the effects of two physical crosslinking methods, ultraviolet irradiation (UV) (254 nm) and dehydrothermal (DHT) treatment, on the mechanical properties and molecular integrity of collagen fibers extruded from an acidic dispersion of type I bovine dermal collagen. Collagen fibers exposed to UV irradiation for 15 min had ultimate tensile… CONTINUE READING

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