Physical break-down of the classical view on cancer cell invasion and metastasis.

@article{Mierke2013PhysicalBO,
  title={Physical break-down of the classical view on cancer cell invasion and metastasis.},
  author={Claudia Tanja Mierke},
  journal={European journal of cell biology},
  year={2013},
  volume={92 3},
  pages={89-104}
}
Eight classical hallmarks of cancer have been proposed and are well-defined by using biochemical or molecular genetic methods, but are not yet precisely defined by cellular biophysical processes. To define the malignant transformation of neoplasms and finally reveal the functional pathway, which enables cancer cells to promote cancer progression, these classical hallmarks of cancer require the inclusion of specific biomechanical properties of cancer cells and their microenvironment such as the… CONTINUE READING

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