Physical and Psychological Stress in Rats Enhances Colonic Epithelial Permeability via Peripheral CRH

Abstract

Stress may be a contributing factor in intestinal inflammatory disease; however, the underlying mechanisms have not been elucidated. We previously reported that acute stress altered jejunal epithelial physiology. In this study, we examined both physical and psychological stress-induced functional changes in colonic mucosa. Colonic mucosal tissue from rats… (More)
DOI: 10.1023/A:1013204612762

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