Physical activity as an exogenous risk factor in motor neuron disease (MND): A review of the evidence

@article{Harwood2009PhysicalAA,
  title={Physical activity as an exogenous risk factor in motor neuron disease (MND): A review of the evidence},
  author={Ceryl A Harwood and C. Mcdermott and P. Shaw},
  journal={Amyotrophic Lateral Sclerosis},
  year={2009},
  volume={10},
  pages={191 - 204}
}
  • Ceryl A Harwood, C. Mcdermott, P. Shaw
  • Published 2009
  • Psychology, Medicine
  • Amyotrophic Lateral Sclerosis
  • Motor neuron disease (MND) is a devastating neurodegenerative condition associated with considerable disability and a poor prognosis. Despite improvements in symptomatic management in recent years, few therapies are available which modify survival. However, the challenge to find successful treatments would be greatly assisted by clearer elucidation of the underlying pathoaetiology. Many potential exogenous risk factors have been proposed as part of a gene-environment interaction in the… CONTINUE READING
    85 Citations
    The quest for exogenous risk factors in ALS: Is there a place for physical activity?
    • A. Chiò
    • Medicine
    • Amyotrophic lateral sclerosis & frontotemporal degeneration
    • 2016
    • 1
    Physical fitness and amyotrophic lateral sclerosis: dangerous liaisons or common genetic pathways?
    • A. Chiò, G. Mora
    • Medicine
    • Journal of Neurology, Neurosurgery & Psychiatry
    • 2012
    • 15
    Long-term physical activity: an exogenous risk factor for sporadic amyotrophic lateral sclerosis?
    • 20
    • PDF
    Physical activity and risk of Amyotrophic Lateral Sclerosis in a prospective cohort study
    • 36
    • PDF
    New insights on physical activity and amyotrophic lateral sclerosis
    • 1

    References

    SHOWING 1-10 OF 146 REFERENCES
    Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target.
    • 376
    • PDF
    Amyotrophic lateral sclerosis in an Italian professional soccer player.
    • 39
    Sports and trauma in amyotrophic lateral sclerosis revisited
    • C. Armon
    • Medicine
    • Journal of the Neurological Sciences
    • 2007
    • 85
    Excitotoxicity and Amyotrophic Lateral Sclerosis
    • 143
    Analysis of factors that modify susceptibility and rate of progression in amyotrophic lateral sclerosis (ALS)
    • 96
    Soccer, neurotrauma and amyotrophic lateral sclerosis: is there a connection?
    • 57