Physical activity and the endocannabinoid system: an overview

@article{Tantimonaco2014PhysicalAA,
  title={Physical activity and the endocannabinoid system: an overview},
  author={Mirko Tantimonaco and Roberta Ceci and Stefania Sabatini and Maria Valeria Catani and Antonello Rossi and Valeria Gasperi and Mauro Maccarrone},
  journal={Cellular and Molecular Life Sciences},
  year={2014},
  volume={71},
  pages={2681-2698}
}
Recognized as a “disease modifier”, physical activity (PA) is increasingly viewed as a more holistic, cost-saving method for prevention, treatment and management of human disease conditions. The traditional view that PA engages the monoaminergic and endorphinergic systems has been challenged by the discovery of the endocannabinoid system (ECS), composed of endogenous lipids, their target receptors, and metabolic enzymes. Indeed, direct and indirect evidence suggests that the ECS might mediate… 
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