Physical activity, smoking, and genetic predisposition to obesity in people from Pakistan: the PROMIS study

@article{Ahmad2015PhysicalAS,
  title={Physical activity, smoking, and genetic predisposition to obesity in people from Pakistan: the PROMIS study},
  author={S. Ahmad and W. Zhao and F. Renstr{\"o}m and A. Rasheed and M. Samuel and Mozzam Zaidi and N. Shah and N. H. Mallick and K. Zaman and M. Ishaq and S. Z. Rasheed and Fazal-ur-Rheman Memon and B. Hanif and M. S. Lakhani and F. Ahmed and S. Kazmi and P. Frossard and P. Franks and D. Saleheen},
  journal={BMC Medical Genetics},
  year={2015},
  volume={16}
}
  • S. Ahmad, W. Zhao, +16 authors D. Saleheen
  • Published 2015
  • Medicine
  • BMC Medical Genetics
  • BackgroundMultiple genetic variants have been reliably associated with obesity-related traits in Europeans, but little is known about their associations and interactions with lifestyle factors in South Asians.MethodsIn 16,157 Pakistani adults (8232 controls; 7925 diagnosed with myocardial infarction [MI]) enrolled in the PROMIS Study, we tested whether: a) BMI-associated loci, individually or in aggregate (as a genetic risk score - GRS), are associated with BMI; b) physical activity and smoking… CONTINUE READING
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