Physical Interaction of RECQ5 Helicase with RAD51 Facilitates Its Anti-recombinase Activity*

@inproceedings{Schwendener2010PhysicalIO,
  title={Physical Interaction of RECQ5 Helicase with RAD51 Facilitates Its Anti-recombinase Activity*},
  author={Sybille Schwendener and Steven Raynard and Shreya Paliwal and Anita S M Cheng and Radhakrishnan Kanagaraj and Igor V. Shevelev and Jeremy M Stark and Patrick Sung and Pavel Janscak},
  booktitle={The Journal of biological chemistry},
  year={2010}
}
Homologous recombination (HR) provides an efficient mechanism for error-free repair of DNA double-strand breaks (DSBs). However, HR can be also harmful as inappropriate or untimely HR events can give rise to lethal recombination intermediates and chromosome rearrangements. A critical step of HR is the formation of a RAD51 filament on single-stranded (ss)DNA… CONTINUE READING