Physical Activity is Associated with Better Neurocognitive and Everyday Functioning Among Older Adults with HIV Disease

Abstract

We examined the association between physical activity (PA), neurocognitive impairment (NCI), and instrumental activities of daily living (IADLs) among older HIV+ persons. One hundred older HIV+ adults completed the International Physical Activity Questionnaire, a neurocognitive battery, and IADL scale. Higher levels of moderate PA were associated with lower odds of NCI (p = 0.01), even when covariates were modeled. The association between moderate PA and NCI was driven by executive function (p = 0.04). Higher levels of moderate PA were also associated with lower odds of IADL Dependence (p = 0.03), although this fell to a trend (p = 0.08) when including covariates. Follow-up analysis showed those with both NCI and IADL Dependence had lower moderate PA than those with neither (p = 0.03). While these cross-sectional findings suggest PA is associated with better neurocognitive and everyday functioning in older HIV+ adults, longitudinal studies utilizing objective PA methods are needed to evaluate directionality and mechanisms.

DOI: 10.1007/s10461-015-1024-z

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Cite this paper

@article{Fazeli2015PhysicalAI, title={Physical Activity is Associated with Better Neurocognitive and Everyday Functioning Among Older Adults with HIV Disease}, author={Pariya Fazeli and Mar{\'i}a J. Marquine and C. Dufour and Brook L. Henry and Jessica L. Montoya and Ben D Gouaux and Raeanne C Moore and Scott L Letendre and Steven Paul Woods and Igor Grant and Dilip V. Jeste and David J. Moore}, journal={AIDS and Behavior}, year={2015}, volume={19}, pages={1470-1477} }