Physical Activity and Stroke Risk: A Meta-Analysis

@article{Lee2003PhysicalAA,
  title={Physical Activity and Stroke Risk: A Meta-Analysis},
  author={Chong-Do Lee and Aaron R. Folsom and Steven N. Blair},
  journal={Stroke: Journal of the American Heart Association},
  year={2003},
  volume={34},
  pages={2475-2481}
}
Background and Purpose— Whether physical activity reduces stroke risk remains controversial. We used a meta-analysis to examine the overall association between physical activity or cardiorespiratory fitness and stroke incidence or mortality. Methods— We searched MEDLINE from 1966 to 2002 and identified 23 studies (18 cohort and 5 case-control) that met inclusion criteria. We estimated the overall relative risk (RR) of stroke incidence or mortality for highly and moderately active individuals… 

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References

SHOWING 1-10 OF 61 REFERENCES

Physical Activity and Stroke Mortality in Women

Examination of the association between different levels of leisure-time physical activity and stroke mortality in middle-aged and elderly women in Norway found that the relative risk of dying decreased with increasing physical activity, after adjustment for potentially confounding factors.

Physical activity and risk of stroke in women.

Physical activity, including moderate-intensity exercise such as walking, is associated with substantial reduction in risk of total and ischemic stroke in a dose-response manner, and data indicate that physical activity was not significantly associated with subarachnoid hemorrhage or intracerebral hemorrhage.

Physical activity and stroke incidence: the Harvard Alumni Health Study.

Physical activity is associated with decreased stroke risk in men, and Climbing stairs and activities of at least moderate intensity each showed U-shaped relations to stroke risk, with the risk being significantly lower at the nadir of the curve.

Physical activity and stroke risk: the Framingham Study.

Results indicate that medium and high levels of physical activity among men are protective against stroke relative to low levels, while adjusted analyses showed no significant protective effect in women.

Physical activity and ischemic stroke risk. The atherosclerosis risk in communities study.

The findings suggest that physical activity was weakly associated with a reduced risk of ischemic stroke among middle-aged adults.

Exercise and risk of stroke in male physicians.

In the present study, the inverse association with physical activity appeared to be mediated through beneficial effects on body weight, blood pressure, serum cholesterol, and glucose tolerance, and apart from its favorable influences on these variables, physical activity had no significant residual association with stroke incidence.

Leisure-time physical activity and ischemic stroke risk: the Northern Manhattan Stroke Study.

Leisure-time physical activity was related to a decreased occurrence of ischemic stroke in the authors' elderly, multiethnic, urban subjects, and more emphasis on physical activity in stroke prevention campaigns is needed among the elderly.

Physical activity and stroke in British middle aged men.

Moderate physical activity significantly reduces the risk of stroke and heart attacks in men both with and without pre-existing ischaemic heart disease, and should be encouraged without restriction.

Physical activity and stroke mortality in women. Ten-year follow-up of the Nord-Trondelag health survey, 1984-1986.

Evidence that physical activity should be part of a primary prevention strategy against stroke in women is strengthened, as physical activity was associated with reduced risk of death from stroke in middle-aged and elderly women.

Cardiorespiratory fitness and stroke mortality in men.

Moderate and high levels of cardiorespiratory fitness were associated with lower risk of stroke mortality in men in the Aerobics Center Longitudinal study population.
...