Phylogeny of Horse Chromosome 5q in the Genus Equus and Centromere Repositioning

@article{Piras2009PhylogenyOH,
  title={Phylogeny of Horse Chromosome 5q in the Genus Equus and Centromere Repositioning},
  author={Francesca M Piras and Solomon G Nergadze and Victoria Offredi Poletto and F. Cerutti and Oliver A. Ryder and Tosso Leeb and Elena Raimondi and Elena Giulotto},
  journal={Cytogenetic and Genome Research},
  year={2009},
  volume={126},
  pages={165 - 172}
}
Horses, asses and zebras belong to the genus Equus and are the only extant species of the family Equidae in the order Perissodactyla. In a previous work we demonstrated that a key factor in the rapid karyotypic evolution of this genus was evolutionary centromere repositioning, that is, the shift of the centromeric function to a new position without alteration of the order of markers along the chromosome. In search of previously undiscovered evolutionarily new centromeres, we traced the… 

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References

SHOWING 1-10 OF 35 REFERENCES
Evolutionary movement of centromeres in horse, donkey, and zebra.
Karyotypic relationships of horses and zebras: results of cross-species chromosome painting
TLDR
The comparative maps of equids allow for the unequivocal characterization of chromosomal rearrangements that differentiate the karyotypes of these equid species.
A survey of equid mitochondrial DNA: Implications for the evolution, genetic diversity and conservation of Equus
TLDR
The phylogenetic analysis of the mitochondrial DNA sequences of the control region and 12S rRNA gene provides further evidence that the deepest node in the phylogeny of the extant species is a divergence between twolineages, with the later speciation events of the zebras and asses occurring either as one or more rapid radiations, or withextensive secondary contact after speciation.
Multidirectional cross-species painting illuminates the history of karyotypic evolution in Perissodactyla
TLDR
The first genome-wide comparative chromosome maps of African rhinoceroses, four tapir species, four equine species, and humans are reported, revealing a striking switch between the slowly evolving ceratomorphs and extremely rapidly evolving equids.
FISH analysis comparing genome organization in the domestic horse (Equus caballus) to that of the Mongolian wild horse (E. przewalskii)
TLDR
A comparative gene map between ECA and EPR by FISH mapping 46 domestic horse-derived BAC clones containing genes previously mapped to ECA chromosomes indicated that all ECAand EPR chromosomes were homologous as predicted by GTG banding, but provide new information in that the EPR acrocentric chromosomes EPR23 and E PR24 were shown to be homologues of the ECA metacentric chromosome ECA5.
Karyotypic relationships among Equus grevyi, Equus burchelli and domestic horse defined using horse chromosome arm-specific probes
TLDR
Establishment of the comparative map for E. grevyi and E. burchelli is compared, providing evidence for a very close karyotypic relationship between these two zebra species and the use of arm-specific probes provided more information on the mutual arrangement of the genomes than could be obtained by means of whole-chromosome paints generated by flow sorting.
Comparative cytogenetics of tapirs, genus Tapirus (Perissodactyla, Tapiridae)
TLDR
Future cytogenetic studies of tapirs from the entire range of each of the four species might provide additional insight into their evolutionary biology and aid wildlife conservation efforts aimed at these threatened mammals.
Comparative chromosomal studies of E. caballus (ECA) and E. przewalskii (EPR) in a female F1 hybrid.
  • E. Ahrens, G. Stranzinger
  • Biology
    Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie
  • 2005
TLDR
The formation of a trivalent during meiosis in a male F1 hybrid and the homologies in G-banding patterns suggest that ECA 5 corresponds to two acrocentric EPR chromosomes resulting from a Robertsonian fusion or fission event.
Mitochondrial DNA evolution in the genus Equus.
TLDR
The variation between species supports a divergence of extant lineages from a common ancestor approximately 3.9 Myr before the present, and trees constructed according to the parsimony principle indicate that the three extant zebra species represent a monophyletic group.
Phylogenetic Relationships Within the Genus Equus and the Evolution of α and θ Globin Genes
Abstract. Sequences of the α1, α2 and θ globin genes from six equid species have been determined to investigate relationships within the genus Equus. Analyses using standard phylogenetic methods, or
...
...