Phylogenetic footprinting analysis in the upstream regulatory regions of the Drosophila enhancer of split genes.

@article{Maeder2007PhylogeneticFA,
  title={Phylogenetic footprinting analysis in the upstream regulatory regions of the Drosophila enhancer of split genes.},
  author={Morgan L. Maeder and Benjamin J. Polansky and Bryanne E. Robson and Deborah A. Eastman},
  journal={Genetics},
  year={2007},
  volume={177 3},
  pages={1377-94}
}
During Drosophila development Suppressor of Hairless [Su(H)]-dependent Notch activation upregulates transcription of the Enhancer of split-Complex [E(spl)-C] genes. Drosophila melanogaster E(spl) genes share common transcription regulators including binding sites for Su(H), proneural, and E(spl) basic-helix-loop-helix (bHLH) proteins. However, the expression patterns of E(spl) genes during development suggest that additional factors are involved. To better understand regulators responsible for… CONTINUE READING

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