Phylogenetic dichotomy of nerve glycosphingolipids.

  title={Phylogenetic dichotomy of nerve glycosphingolipids.},
  author={Naomichi Okamura and Michael Stoskopf and F H Hendricks and Yasuo Kishimoto},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={82 20},
Galactocerebrosides and sulfatides are major characteristic components of vertebrate myelin. In contrast, glucocerebroside is the major glycosphingolipid of shrimp nerve. In this study, the concentrations of these glycosphingolipids in the nervous systems of animals from several evolutionary branches were determined by use of high-performance liquid chromatography. In nerves of protostome animals only glucose-containing glycosphingolipids were detected, whereas glycosphingolipids from… CONTINUE READING