Phylogenetic designation of enterovirus 71 genotypes and subgenotypes using complete genome sequences.

@article{Chan2010PhylogeneticDO,
  title={Phylogenetic designation of enterovirus 71 genotypes and subgenotypes using complete genome sequences.},
  author={Yoke Fun Chan and I-ching Sam and Sazaly AbuBakar},
  journal={Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases},
  year={2010},
  volume={10 3},
  pages={404-12}
}
Human enterovirus 71 (EV-71) is genotyped for molecular epidemiological investigation mainly using the two structural genes, VP1 and VP4. Based on these, EV-71 is divided into three genotypes, A, B and C, and within the genotypes B and C, there are further subgenotypes, B1-B5 and C1-C5. Classification using these genes is useful but gives incomplete phylogenetic information. In the present study, the phylogenetic relationships amongst all the known EV-71 and human enterovirus A (HEV-A) isolates… CONTINUE READING

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