Phylogenetic conservation and physical mapping of members of the H6 homeobox gene family

@article{Stadler1995PhylogeneticCA,
  title={Phylogenetic conservation and physical mapping of members of the H6 homeobox gene family},
  author={H. S. Stadler and Jeffrey C Murray and Nancy J. Leysens and Paul J Goodfellow and Michael Solursh},
  journal={Mammalian Genome},
  year={1995},
  volume={6},
  pages={383-388}
}
Homeobox genes represent a class of transcription factors that play key roles in the regulation of embryogenesis and development. Here we report the identification of a homeobox-containing gene family that is highly conserved at both the nucleotide and amino acid levels in a diverse number of species. These species encompass both vertebrate and invertebrate phylogenies, ranging from Homo sapiens to Drosophila melanogaster. In humans, at least two homeobox sequences from this family were… CONTINUE READING