Phylogenetic and 2D/3D Analysis of HCV 1a NS4A Gene/Protein in Pakistani Isolates

@inproceedings{Hussain2015PhylogeneticA2,
  title={Phylogenetic and 2D/3D Analysis of HCV 1a NS4A Gene/Protein in Pakistani Isolates},
  author={Abrar Hussain and Muhammad Idrees and Muhammad Asif and L. Javid Ali and Mahmood Rasool},
  booktitle={Hepatitis monthly},
  year={2015}
}
BACKGROUND The nonstructural protein NS4A of hepatitis C virus is composed of 54 amino acids. This small size protein has vital role in many cellular functions. The most important reported function is being a cofactor of viral enzymes serine protease and helicase. OBJECTIVES The objective of this study was to analyze the phylogenetic variation, its impact in terms of translation and any functional change in protein structure at primary 2D/3D structure using computational tools from Pakistani… CONTINUE READING

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