Phylogenetic analysis of the thiolase family. Implications for the evolutionary origin of peroxisomes

@article{Igual1992PhylogeneticAO,
  title={Phylogenetic analysis of the thiolase family. Implications for the evolutionary origin of peroxisomes},
  author={J Carlos Igual and Carmen Gonz{\'a}lez-Bosch and Joaqu{\'i}n Dopazo and Jos{\'e} E. P{\'e}rez-Ort{\'i}n},
  journal={Journal of Molecular Evolution},
  year={1992},
  volume={35},
  pages={147-155}
}
The thiolase family is a widespread group of proteins present in prokaryotes and three cellular compartments of eukaryotes. This fact makes this family interesting in order to study the evolutionary process of eukaryotes. Using the sequence of peroxisomal thiolase from Saccharomyces cerevisiae recently obtained by us and the other known thiolase sequences, a phylogenetic analysis has been carried out. It shows that all these proteins derived from a primitive enzyme, present in the common… CONTINUE READING

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