• Corpus ID: 21751988

Phylogenetic analysis of basic helix-loop-helix transcription factors in the genome of a typical human-disease vector.

  title={Phylogenetic analysis of basic helix-loop-helix transcription factors in the genome of a typical human-disease vector.},
  author={Meng Chen and Y Dong and Ruixue X. Chang and Qian-Qian Ang and Ran Zhang and Yan-Yan Wu and Yihui Xu and Wen-sheng Lu and Xiao-dong Zheng},
  journal={American journal of translational research},
  volume={8 11},
Ixodes scapularis, the black-legged tick, is one of the most common human-disease vectors and transmits Borrelia species, such as B. burgdorferi, as well as Theileria microti, Anaplasma phagocytophilum, etc. As basic helix-loop-helix (bHLH) transcription factors have been recognized for many years as important regulators of various developmental processes, we performed phylogenetic analysis of the black-legged tick genome in order to identify the number and family of bHLH transcription factors… 

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