Phylogenetic Tree Construction Using Markov Chain Monte Carlo

@article{Li2000PhylogeneticTC,
  title={Phylogenetic Tree Construction Using Markov Chain Monte Carlo},
  author={Shuying S Li and Dennis K. Pearl and Hani Doss},
  journal={Journal of the American Statistical Association},
  year={2000},
  volume={95},
  pages={493 - 508}
}
Abstract We describe a Bayesian method based on Markov chain simulation to study the phylogenetic relationship in a group of DNA sequences. Under simple models of mutational events, our method produces a Markov chain whose stationary distribution is the conditional distribution of the phylogeny given the observed sequences. Our algorithm strikes a reasonable balance between the desire to move globally through the space of phylogenies and the need to make computationally feasible moves in areas… 
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272 Citations
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272 Citations

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