Phylogenetic Tree Construction Using Markov Chain Monte Carlo
@article{Li2000PhylogeneticTC, title={Phylogenetic Tree Construction Using Markov Chain Monte Carlo}, author={Shuying S. Li and Dennis K. Pearl and Hani Doss}, journal={Journal of the American Statistical Association}, year={2000}, volume={95}, pages={493 - 508} }
Abstract We describe a Bayesian method based on Markov chain simulation to study the phylogenetic relationship in a group of DNA sequences. Under simple models of mutational events, our method produces a Markov chain whose stationary distribution is the conditional distribution of the phylogeny given the observed sequences. Our algorithm strikes a reasonable balance between the desire to move globally through the space of phylogenies and the need to make computationally feasible moves in areas…
274 Citations
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