Phylogenetic Diversity of Sponge-Associated Fungi from the Caribbean and the Pacific of Panama and Their In Vitro Effect on Angiotensin and Endothelin Receptors

@article{Bolaos2015PhylogeneticDO,
  title={Phylogenetic Diversity of Sponge-Associated Fungi from the Caribbean and the Pacific of Panama and Their In Vitro Effect on Angiotensin and Endothelin Receptors},
  author={Jessica Bola{\~n}os and Luis F. Le{\'o}n and Edgardo Ochoa and Jos{\'e} Dar{\'i}as and Huzefa A. Raja and Carol A. Shearer and Andrew N. Miller and Patrick M. L. Vanderheyden and Andrea Porras-Alfaro and Catherina C. Caballero-George},
  journal={Marine Biotechnology},
  year={2015},
  volume={17},
  pages={533-564}
}
Fungi occupy an important ecological niche in the marine environment, and marine fungi possess an immense biotechnological potential. This study documents the fungal diversity associated with 39 species of sponges and determines their potential to produce secondary metabolites capable of interacting with mammalian G-protein-coupled receptors involved in blood pressure regulation. Total genomic DNA was extracted from 563 representative fungal strains obtained from marine sponges collected by… CONTINUE READING
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