Phylogenetic Analysis of the Endoribonuclease Dicer Family

  title={Phylogenetic Analysis of the Endoribonuclease Dicer Family},
  author={Zeqian Gao and Miao Wang and David Blair and Yadong Zheng and Yong-xi Dou},
  booktitle={PloS one},
Dicers are proteins of the ribonuclease III family with the ability to process dsRNA, involved in regulation of gene expression at the post-transcriptional level. Dicers are conserved from basal metazoans to higher metazoans and contain a number of functional domains that interact with dsRNA. The completed genome sequences of over 34 invertebrate species allowed us to systematically investigate Dicer genes over a diverse range of phyla. The majority of invertebrate Dicers clearly fell into the… CONTINUE READING