Phyllanthus amarus has anti-inflammatory potential by inhibition of iNOS, COX-2, and cytokines via the NF-kappaB pathway.

@article{Kiemer2003PhyllanthusAH,
  title={Phyllanthus amarus has anti-inflammatory potential by inhibition of iNOS, COX-2, and cytokines via the NF-kappaB pathway.},
  author={Alexandra K Kiemer and Thomas Hartung and Christian Huber and Angelika M. Vollmar},
  journal={Journal of hepatology},
  year={2003},
  volume={38 3},
  pages={289-97}
}
BACKGROUND/AIMS Phyllanthus amarus is a herbal medicine traditionally applied in the treatment of viral hepatitis. Aim of this study was to investigate potential anti-inflammatory properties of standardized P. amarus extracts concerning a potential influence of P. amarus on endotoxin-induced nitric oxide synthase (iNOS), cyclooxygenase (COX-2), and cytokine production in vivo and in vitro. METHODS Investigations were performed in rat Kupffer cells (KC), in RAW264.7 macrophages, in human whole… CONTINUE READING

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