Phycocyanin induces apoptosis and enhances the effect of topotecan on prostate cell line LNCaP.

@article{Gantar2012PhycocyaninIA,
  title={Phycocyanin induces apoptosis and enhances the effect of topotecan on prostate cell line LNCaP.},
  author={Miroslav Gantar and S. Dhandayuthapani and Appu Rathinavelu},
  journal={Journal of medicinal food},
  year={2012},
  volume={15 12},
  pages={1091-5}
}
C-phycocyanin (C-PC) from Spirulina has been previously shown to have anticancer properties. Here, we report on anticancer activity of C-PC that was isolated from the novel cyanobacterium Limnothrix sp. 37-2-1. C-PC from this organism exhibited anticancer properties in our in vitro systems; however, the required doses were well above the range of anticancer drugs normally used. Therefore, we conducted several experiments to test whether lower-than-usual doses of the anticancer drug topotecan… CONTINUE READING

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