Phototoxicity and Environmental Transformation of Polycyclic Aromatic Hydrocarbons (PAHs)—Light-Induced Reactive Oxygen Species, Lipid Peroxidation, and DNA Damage

@article{Fu2012PhototoxicityAE,
  title={Phototoxicity and Environmental Transformation of Polycyclic Aromatic Hydrocarbons (PAHs)—Light-Induced Reactive Oxygen Species, Lipid Peroxidation, and DNA Damage},
  author={P. Fu and Q. Xia and X. Sun and Hongtao Yu},
  journal={Journal of Environmental Science and Health, Part C},
  year={2012},
  volume={30},
  pages={1 - 41}
}
  • P. Fu, Q. Xia, +1 author Hongtao Yu
  • Published 2012
  • Chemistry, Medicine
  • Journal of Environmental Science and Health, Part C
  • Polycyclic aromatic hydrocarbons (PAHs) are a class of mutagenic and tumorigenic environmental contaminants. Although the mechanisms by which PAHs induce cancer in experimental animals have been extensively studied and the metabolic activation pathways have been determined, the environmental fate of PAHs and the phototoxicity exerted by PAHs, as well as their photoreaction products formed in the environment, have received much less attention. In this review, the formation of oxygenated PAHs… CONTINUE READING
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