Phototoxicity and Environmental Transformation of Polycyclic Aromatic Hydrocarbons (PAHs)—Light-Induced Reactive Oxygen Species, Lipid Peroxidation, and DNA Damage
@article{Fu2012PhototoxicityAE, title={Phototoxicity and Environmental Transformation of Polycyclic Aromatic Hydrocarbons (PAHs)—Light-Induced Reactive Oxygen Species, Lipid Peroxidation, and DNA Damage}, author={P. Fu and Q. Xia and X. Sun and Hongtao Yu}, journal={Journal of Environmental Science and Health, Part C}, year={2012}, volume={30}, pages={1 - 41} }
Polycyclic aromatic hydrocarbons (PAHs) are a class of mutagenic and tumorigenic environmental contaminants. Although the mechanisms by which PAHs induce cancer in experimental animals have been extensively studied and the metabolic activation pathways have been determined, the environmental fate of PAHs and the phototoxicity exerted by PAHs, as well as their photoreaction products formed in the environment, have received much less attention. In this review, the formation of oxygenated PAHs… CONTINUE READING
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References
SHOWING 1-10 OF 232 REFERENCES
Photoirradiation of representative polycyclic aromatic hydrocarbons and twelve isomeric methylbenz[a]anthracene with UVA light: formation of lipid peroxidation
- Chemistry, Medicine
- Toxicology and industrial health
- 2006
- 17
Photoirradiation of polycyclic aromatic hydrocarbons with UVA light - a pathway leading to the generation of reactive oxygen species, lipid peroxidation, and dna damage.
- Chemistry, Medicine
- International journal of environmental research and public health
- 2006
- 55
- PDF
Photoirradiation of polycyclic aromatic hydrocarbon diones by UVA light leading to lipid peroxidation.
- Chemistry, Medicine
- Chemosphere
- 2011
- 12
Photoinduced toxicity of polycyclic aromatic hydrocarbons to Daphnia magna: ultraviolet-mediated effects and the toxicity of polycyclic aromatic hydrocarbon photoproducts.
- Chemistry, Medicine
- Environmental toxicology and chemistry
- 2006
- 91
UVA Photoirradiation of Oxygenated Benz[a]anthracene and 3-Methylcholanthene - Generation of Singlet Oxygen and Induction of Lipid Peroxidation
- Chemistry, Medicine
- International journal of environmental research and public health
- 2008
- 16
- PDF
UVA Photoirradiation of Halogenated-Polycyclic Aromatic Hydrocarbons Leading to Induction of Lipid Peroxidation
- Chemistry, Medicine
- International journal of environmental research and public health
- 2006
- 11
- PDF
ENVIRONMENTAL CARCINOGENIC POLYCYCLIC AROMATIC HYDROCARBONS: PHOTOCHEMISTRY AND PHOTOTOXICITY
- Chemistry, Medicine
- Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
- 2002
- 269
UVA Photoirradiation of Methylated Benzo[a]pyrene and Benzo[e]pyrene leading to Induction of Lipid Peroxidation
- Chemistry, Medicine
- International journal of environmental research and public health
- 2007
- 8
- PDF
Benzo[a]Pyrene Diones are Produced by Photochemical and Enzymatic Oxidation and Induce Concentration-Dependent Decreases in the Proliferative State of Human Pulmonary Epithelial Cells
- Chemistry, Medicine
- Journal of toxicology and environmental health. Part A
- 2003
- 41
DNA damage induced by coexposure to PAHs and light.
- Chemistry, Medicine
- Environmental toxicology and pharmacology
- 2007
- 68