Phototoxic potential of quinolones.

@article{Crdenas1991PhototoxicPO,
  title={Phototoxic potential of quinolones.},
  author={A. C{\'a}rdenas and F. Vargas and E. Fern{\'a}ndez and M. Hidalgo},
  journal={Journal of photochemistry and photobiology. B, Biology},
  year={1991},
  volume={10 3},
  pages={
          249-55
        }
}
The photohaemolytic potentials of the quinolones oxolinic acid, pipemidic acid, rosoxacin, norfloxacin, ciprofloxacin and M-193324 (synthesis intermediary) were evaluated and compared with the photohaemolysis induced by nalidixic acid. Quinolones with a piperazine group in position 7 (pipemidic acid, norfloxacin and ciprofloxacin) did not induce photohaemolysis. However, oxolinic acid, rosoxacin and M-193324 produced a concentration- and oxygen-dependent photohaemolysis. Ascorbic acid… Expand
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