Phototherapy Increases Hemoglobin Degradation and Bilirubin Production in Preterm Infants

Abstract

OBJECTIVE:To compare hemoglobin degradation and bilirubin production before and during phototherapy in preterm infants.BACKGROUND:Hemoglobin is catabolized into globin and heme, which is degraded by microsomal heme oxygenase into equimolar carbon monoxide and biliverdin. Biliverdin is then reduced into bilirubin. CO is excreted exclusively by the lungs… (More)
DOI: 10.1038/sj.jp.7200184

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