Photosensitizers related to purpurin-18-N-alkylimides: a comparative in vivo tumoricidal ability of ester versus amide functionalities.

@article{Zheng2000PhotosensitizersRT,
  title={Photosensitizers related to purpurin-18-N-alkylimides: a comparative in vivo tumoricidal ability of ester versus amide functionalities.},
  author={Gang Zheng and William R Potter and Adam B Sumlin and Thomas J. Dougherty and Ravindra K Pandey},
  journal={Bioorganic & medicinal chemistry letters},
  year={2000},
  volume={10 2},
  pages={123-7}
}
For a comparative study, 3-(alkyloxyethyl)-3-devinylpurpurin-18-N-hexylimides with ester and amide functionalities were investigated for tumor selectivity and in vivo photosensitizing efficacy. Compared to amide analogues, the related photosensitizers with ester functionalities were found to be more effective. Among these compounds the 3-devinyl-(3… CONTINUE READING