Photorepair of nonadjacent pyrimidine dimers by DNA photolyase.

@article{Kim1995PhotorepairON,
  title={Photorepair of nonadjacent pyrimidine dimers by DNA photolyase.},
  author={Soowon Kim and Aziz Sancar},
  journal={Photochemistry and photobiology},
  year={1995},
  volume={61 2},
  pages={
          171-4
        }
}
Photolyases reverse the harmful effects of UV light on cells by converting pyrimidine dimers (Pyr[]Pyr) into two pyrimidine monomers by utilizing near-UV and visible light. Previous work has shown that photolyase repairs T[c,s]T and T[t,s]T in DNA as well as U[]U in RNA, all of which are formed by joining the two adjacent pyrimidines in a light-dependent reaction. In this report, we show that Pyr[]Pyr formed in nonadjacent pyrimidines are also substrates for DNA photolyase. 
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