Photoprotective potential of lycopene, beta-carotene, vitamin E, vitamin C and carnosic acid in UVA-irradiated human skin fibroblasts.

@article{Offord2002PhotoprotectivePO,
  title={Photoprotective potential of lycopene, beta-carotene, vitamin E, vitamin C and carnosic acid in UVA-irradiated human skin fibroblasts.},
  author={Elizabeth A Offord and Josselin Gautier and Ornella Avanti and Corinne Scaletta and Frank Runge and Klaus Kraemer and Lee Ann Applegate},
  journal={Free radical biology & medicine},
  year={2002},
  volume={32 12},
  pages={1293-303}
}
The photoprotective potential of the dietary antioxidants vitamin C, vitamin E, lycopene, beta-carotene, and the rosemary polyphenol, carnosic acid, was tested in human dermal fibroblasts exposed to ultraviolet-A (UVA) light. The carotenoids were prepared in special nanoparticle formulations together with vitamin C and/or vitamin E. Nanoparticle formulations, in contrast to dimethylsulphoxide, stablized lycopene in the cell culture medium and allowed efficient cellular uptake. The presence of… CONTINUE READING

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