Photophobe (Ppb), a Drosophila mutant with a reversed sign of phototaxis; the mutation shows an allele-specific interaction with sevenless.

@article{Ballinger1988PhotophobeA,
  title={Photophobe (Ppb), a Drosophila mutant with a reversed sign of phototaxis; the mutation shows an allele-specific interaction with sevenless.},
  author={Dennis G. Ballinger and Seymour Benzer},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1988},
  volume={85 11},
  pages={
          3960-4
        }
}
We have isolated a dominant behavioral mutation, Photophobe (Ppb), on the second chromosome of Drosophila melanogaster. Although wild-type flies are attracted towards green light, flies homozygous for the Ppb mutation avoid it over an intensity range of six logarithms. Ppb interacts in a dominant way with mutations in the sevenless (sev) gene, an X-chromosomal gene necessary for photoreceptor cell 7 differentiation in the Drosophila retina. Specific alleles of sev alter the Ppb behavioral… CONTINUE READING

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