Photoperiod-induced change in responsiveness of the hypothalamic-pituitary axis to exogenous 5 alpha-dihydrotestosterone and 17 beta-estradiol in castrated male hamsters.


Exposure to short day lengths for 9 weeks renders the hypothalamic-putuitary axis of the castrate hamster extremely responsive to the negative feedback effect of exogenous testosterone. The systemic and/or local conversion of testosterone to 5 alpha-dihydrotestosterone (5 alpha-DHT) or 17 beta-estradiol (E2) is considered to be an important step in its… (More)


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