Photon Emissions as Differential Indicators for Different Components of Protein Kinase A (PKA) in Transfected Murine Melanoma Cells

  title={Photon Emissions as Differential Indicators for Different Components of Protein Kinase A (PKA) in Transfected Murine Melanoma Cells},
  author={Blake T. Dotta and Carly A. Buckner and Robert M. Lafrenie and Michael A. Persinger},
  journal={Archives in Cancer Research},
Increased emissions of photons or shifts in spectral power densities of photons have been reliably measured from malignant cells compared to non-malignant cells. Previous experiments have shown that specific wavelengths within the visible spectrum emitted from melanoma cells were associated with the activation or inhibition of specific molecular structures or pathways. To discern if numbers of photons could differentiate the dynamic state of a critical protein (enzyme), Protein… 
1 Citations

Figures from this paper

Bacterial biophotons as non‐local information carriers: Species‐specific spectral characteristics of a stress response
These and the subsequent results of discriminant functions suggest that bacteria may release biophotons as a non‐local communication system in response to stress, and that these biophOTons are species specific.


Shifting wavelengths of ultraweak photon emissions from dying melanoma cells: their chemical enhancement and blocking are predicted by Cosic’s theory of resonant recognition model for macromolecules
The greater-than-expected photon counts compared with raw measures through the various filters, which also function as reflective material to other photons, suggest that photons of different wavelengths might be self-stimulatory and could play a significant role in cell-to-cell communication.
Only 1% Melanoma Proportion in Non-Malignant Cells Exacerbates Photon Emissions: Implications for Tumor Growth and Metastases
Only 1% of malignant cells in a normal aggregate resulted in conspicuously increased numbers of photon emissions and spectral power spectra that often reflect a total malignant cell population.
Biophoton emissions from cell cultures: biochemical evidence for the plasma membrane as the primary source.
The results suggested the most probable origin of the photon emission was the plasma cell membrane, and measures from cells synchronized at the M- and S-phase supported this inference.
Photon emission in tumor biology
This review reports on the different aspects of spontaneous and induced photon emission of tumor cells as compared to normal cells.
Cellular Communication through Light
The study finds that cells can have an influence on other cells even when separated with a glass barrier, thereby disabling molecule diffusion through the cell-containing medium and hints that photon-triggering is a fine tuning principle in cell chemistry.
Spontaneous Photon Emissions in Photoreceptors: Potential Convergence of Arrhenius Reactions and the Latency for Rest Mass Photons to Accelerate to Planck Unit Energies
Spontaneous or phasic voltage shifts normally occur across the plasma membranes of photoreceptors without impingement from external photons on average once every ~38 s (26 mHz).  There have been
Role of Raf-1 and FAK in cell density-dependent regulation of integrin-dependent activation of MAP kinase.
The results suggest that the active form of Raf-1 may interrupt cell-cell contact inhibition by promoting alphav integrin expression, which has been implicated in cell aggregation.
"Doubling" of local photon emissions when two simultaneous, spatially-separated, chemiluminescent reactions share the same magnetic field configurations
The aim of the present experiments was to discern if the “entanglement”-like photon emissions from pairs of cell cultures or human brains separated by significant distances but sharing the same
Molecular Biology of the Cell
  • J. Davies
  • Biology
    Bristol Medico-Chirurgical Journal
  • 1983
This is undoubtedly a landmark for the student and his teacher in the field of preclinical medicine, and the successful texts in these areas eschew traditional academic contrapuntal argument.