Photomediated Reactive Oxygen Species-Generable Nanoparticles for Triggered Release and Endo/Lysosomal Escape of Drug upon Attenuated Single Light Irradiation.

@article{Seo2015PhotomediatedRO,
  title={Photomediated Reactive Oxygen Species-Generable Nanoparticles for Triggered Release and Endo/Lysosomal Escape of Drug upon Attenuated Single Light Irradiation.},
  author={Eun Ha Seo and Chung-Sung Lee and Kun Na},
  journal={Advanced healthcare materials},
  year={2015},
  volume={4 18},
  pages={
          2822-30
        }
}
  • Eun Ha Seo, Chung-Sung Lee, Kun Na
  • Published in Advanced healthcare materials 2015
  • Materials Science, Medicine
  • Nanoparticles with "smart" stimuli-responsive materials and multiple therapeutic strategies in a single delivery platform have emerged for highly efficient cancer therapy. Here, photomediated reactive oxygen species (ROS)-generable nanoparticles are designed that can trigger drug release and endo/lysosomal escape upon attenuated single light irradiation, simultaneously, for synergistic chemo-photodynamic ablation. In this study, the self-ROS-generable nanoparticles (SRNs) are prepared from the… CONTINUE READING

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