Photolytic derivatization for improved LCEC determinations of pharmaceuticals in biological fluids.

@article{Selavka1985PhotolyticDF,
  title={Photolytic derivatization for improved LCEC determinations of pharmaceuticals in biological fluids.},
  author={C. Selavka and I. Krull and I. Lurie},
  journal={Journal of chromatographic science},
  year={1985},
  volume={23 11},
  pages={
          499-508
        }
}
  • C. Selavka, I. Krull, I. Lurie
  • Published 1985
  • Chemistry, Medicine
  • Journal of chromatographic science
  • Although electrochemical (EC) methods have been demonstrated to be sensitive and selective, wide use of EC detection in high performance liquid chromatographic (HPLC) assays in forensic and clinical toxicology laboratories has not been forthcoming. This fact is due to the general difficulty involved with the use of reductive EC detection methods, as well as to the lack of EC response in either the oxidative or reductive mode, for a number of classes of drugs having substantial clinical and… CONTINUE READING
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