Photoinactivation of the Coronavirus Surrogate phi6 by Visible Light

@article{Vatter2020PhotoinactivationOT,
  title={Photoinactivation of the Coronavirus Surrogate phi6 by Visible Light},
  author={Petra Vatter and Katharina Hoenes and Martin Hessling},
  journal={Photochemistry and Photobiology},
  year={2020},
  volume={97}
}
To stop the coronavirus spread, new inactivation approaches are being sought that can also be applied in the presence of humans or even on humans. Here, we investigate the effect of visible violet light with a wavelength of 405 nm on the coronavirus surrogate phi6 in two aqueous solutions that are free of photosensitizers. A dose of 1300 J cm−2 of 405 nm irradiation reduces the phi6 plaque‐forming unit concentration by three log‐levels. The next step should be similar visible light… 
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21 Citations
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21 Citations

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The use of nano-monocaprin (NMC) in inhibiting enveloped and unenveloped bacteriophages and to determine if NMC is toxic to mammalian cells, used MTS assay to assess its IC50 for HPDE and HeLa cell lines.

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It is suggested that amoebae could contribute to the environmental persistence of SARS-CoV-2, including disinfection processes, and could be a successful model system for understanding respiratory virus-eukaryotic biology at the cellular and molecular levels.

Bacteriophage Phi 6 as Surrogate and Human-Harmless Viruses to Study Anti-SARS-CoV-2 Approaches

The use of phage Φ 6 seems to be useful as coronavirus surrogate to assess the effectiveness of anti-SARS-CoV-2 approaches, providing important insights concerning COVID-19 pandemic and human public health.

Development and verification of a test rig for inactivation of bacteria and (corona-) viruses by UVC air disinfection systems

Abstract The ongoing coronavirus pandemic spreads through airborne transmission and is therefore difficult to contain. However, coronaviruses are highly sensitive to UVC, so UVC air disinfection…

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