Photoepilation with a diode laser vs. intense pulsed light: a randomized, intrapatient left‐to‐right trial

  title={Photoepilation with a diode laser vs. intense pulsed light: a randomized, intrapatient left‐to‐right trial},
  author={Annette Klein and Susanne Steinert and Wolf Baeumler and M{\'i}chael Landthaler and Philipp Babilas},
  journal={British Journal of Dermatology},
Background  Safe and efficient options for removing unwanted hair are in great demand. Laser devices and intense pulsed light (IPL) sources are the most commonly used treatment modalities. Yet, only a few randomized controlled trials (RCTs) comparing laser and IPL devices are available, and RCTs with long‐term results are missing from the literature. 

Fixed, low radiant exposure vs. incremental radiant exposure approach for diode laser hair reduction: a randomized, split axilla, comparative single‐blinded trial

Diode lasers are the most commonly used treatment modalities for unwanted hair reduction but not a single randomized controlled trial (RCT) compared the impact of various laser parameters, especially radiant exposure, onto efficacy, tolerability and safety of laser hair reduction.

Intense Pulsed Light Therapy

Intense pulsed light systems are a safe and efficient treatment option for non-ablative skin rejuvenation, hair removal, and the removal of pigmented and vascular lesions.

Side effects from intense pulsed light: Importance of skin pigmentation, fluence level and ultraviolet radiation—A randomized controlled trial

The objective of this study was to assess the contribution of skin pigmentation, fluence level, and ultraviolet radiation (UVR) on IPL‐induced side effects.

Photoepilation and Skin Photorejuvenation: An Update

The strongest advantages of the IPL technologies are robust technology, versatility, lower purchase price, and the negligible risk of serious adverse effects in the hands of skilled and experienced operators.


Both tested sources proved the safety of intense pulsed light hair removal and patient satisfaction scores were in agreement with the treatment efcacy, and the incidence of side effects has no difference between devices.

New lasers and light sources – old and new risks?

While fractional lasers used to be employed to merely treat wrinkles, the same devices have now become important tools in the treatment of scars, field cancerization, and epithelial tumors.

Current Indications and New Applications of Intense

The nonablative nature of IPL makes it an increasingly attractive alter- native for patients unwilling to accept the adverse effects associated with other procedures, which additionally require prolonged absence from work and social activities.

Comparison of the Effect of Diode Laser Versus Intense Pulsed Light in Axillary Hair Removal

Both diode laser and the IPL are effective, safe, and able to produce lasting results in axillary hair removal.

Efficacy of lasers and light sources in long-term hair reduction: a systematic review

In conclusion, greater long-term hair reduction was observed on body sites with longer hair growth cycles, taking into account variations in body site-specific variations in hair growthcycles.



Long‐pulsed Nd:YAG laser vs. intense pulsed light for hair removal in dark skin: a randomized controlled trial

This work has shown that laser treatment of darker skin phototypes is particularly challenging because absorption of laser energy by the targeted hairs is compromised by an increased concentration of epidermal melanin.

Photoepilation with variable pulsed light in non‐facial body areas: evaluation of efficacy and safety

This work evaluated VPL for safety and long‐term efficacy in non‐facial hair removal and found it to be effective in both short and long-term terms.

Efficacy of long‐ and short pulse alexandrite lasers compared with an intense pulsed light source for epilation: a study on 532 sites in 389 patients

Hair induction at the borders of the treated area on the face and neck was seen only with the LP‐Alex, and correlated statistically significantly with any episode of severe erythema, crusting or hyperpigmentation.

Laser Hair Removal: Comparison of Long‐Pulsed Nd YAG, Long‐Pulsed Alexandrite, and Long‐Pulsed Diode Lasers

Comparison of Long‐Pulsed Diode and Long‐Pulsed Alexandrite Lasers for Hair Removal: A Long‐Term Clinical and Histologic Study

  • C. HandrickT. Alster
  • Medicine
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • 2001
While long-term hair reduction can be obtained in most patients after a series of laser treatments, partial hair regrowth is typical within 6 months, suggesting the need for additional treatments to improve the rate of permanent hair removal.

Axillary hair removal with 1064‐nm Nd:YAG laser increases sweat production

This data indicates that changes in sweating have not previously been reported and could be a cause for concern for the safety and efficacy of laser systems used for hair removal.

Within-patient right-left blinded comparison of diode (810 nm) laser therapy and intense pulsed light therapy for hair removal

Both laser and IPL reduced the hair count substantially; laser vs control was significant at P’= 0.028, but IPL vs control had P =‬0.13, suggesting that more subjects or more treatments were required if statistical significance were to be achieved.

Laser Hair Removal with Alexandrite versus Diode Laser Using Four Treatment Sessions: 1‐Year Results

Both the alexandrite and diode lasers in this 12-month study produced excellent long-term hair reductions.

Hair removal in hirsute women with normal testosterone levels: a randomized controlled trial of long‐pulsed diode laser vs. intense pulsed light

Little evidence exists regarding efficacy of hair removal in this specific population and no data are available for patients with verified normal testosterone levels, so there is no guarantee that hair removal will help women with androgen disturbances.

Laser and photoepilation for unwanted hair growth.

There appeared to be a short-term effect of approximately 50% hair reduction with alexandrite and diode lasers up to six months after treatment, whereas little evidence was obtained for an effect of intense pulsed light, neodymium:YAG or ruby lasers.