Photodynamic therapy with topical methyl aminolevulinate for actinic keratosis: results of a prospective randomized multicenter trial.

@article{Pariser2003PhotodynamicTW,
  title={Photodynamic therapy with topical methyl aminolevulinate for actinic keratosis: results of a prospective randomized multicenter trial.},
  author={David M. Pariser and Nicholas J. Lowe and Daniel M Stewart and Michael T Jarratt and Anne W Lucky and Robert J. Pariser and Paul S. Yamauchi},
  journal={Journal of the American Academy of Dermatology},
  year={2003},
  volume={48 2},
  pages={227-32}
}
BACKGROUND Photodynamic therapy (PDT) is a promising new treatment modality for actinic keratoses. Methyl aminolevulinate (MAL) (Metvix, PhotoCure, Oslo, Norway) leads to selective accumulation of photoactive porphyrins in premalignant skin lesions and makes the lesions susceptible to phototoxic effects on illumination with red light. OBJECTIVE This multicenter, randomized, double-blind study compared complete response rates, cosmetic outcome, and patient satisfaction for PDT with cream… CONTINUE READING
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