Photodynamic therapy using Photofrin in combination with buthionine sulfoximine (BSO) to treat 9L gliosarcoma in rat brain.

Abstract

BACKGROUND AND OBJECTIVE The reactive oxygen mechanisms associated with cell damage after photodynamic therapy (PDT) may be exploited to enhance tumor destruction. Pharmacological reduction of glutathione (GSH), an inhibitor of reactive oxygen species, can be induced by administration of buthionine sulfoximine (BSO). STUDY DESIGN/MATERIALS AND METHODS BSO… (More)

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Cite this paper

@article{Jiang1998PhotodynamicTU, title={Photodynamic therapy using Photofrin in combination with buthionine sulfoximine (BSO) to treat 9L gliosarcoma in rat brain.}, author={F Jiang and Lothar Lilge and M Belcuig and Gurudarshan Singh and Julie Grenier and Y Li and Michael Chopp}, journal={Lasers in surgery and medicine}, year={1998}, volume={23 3}, pages={161-6} }