Photodynamic therapy in lung cancer. A review.

  • David E Ost
  • Published 2003 in Methods in molecular medicine


PDT utilizes photosensitizing agents that are selectively retained by tumors. These agents have high resulting tumor:tissue concentrations but are inactive by themselves. When activated by light, they generate free radicals, resulting in membrane injury, vascular injury, and immune-mediated injury with relatively selective cytotoxicity to tumor cells… (More)