Photodynamic therapy (PDT) of cancer: from local to systemic treatment.

@article{Dbrowski2015PhotodynamicT,
  title={Photodynamic therapy (PDT) of cancer: from local to systemic treatment.},
  author={J. Dąbrowski and L. Arnaut},
  journal={Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology},
  year={2015},
  volume={14 10},
  pages={
          1765-80
        }
}
  • J. Dąbrowski, L. Arnaut
  • Published 2015
  • Medicine
  • Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
Photodynamic therapy (PDT) requires a medical device, a photosensitizing drug and adequate use of both to trigger biological mechanisms that can rapidly destroy the primary tumour and provide long-lasting protection against metastasis. We present a multidisciplinary view of the issues raised by the development of PDT. We show how spectroscopy, photophysics, photochemistry and pharmacokinetics of photosensitizers determine the mechanism of cell death and clinical protocols. Various examples of… Expand
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