Photodynamic therapy: tumor targeting with adenoviral proteins.

@article{Allen1999PhotodynamicTT,
  title={Photodynamic therapy: tumor targeting with adenoviral proteins.},
  author={Cynthia M. Allen and Wesley M. Sharman and Carole La Madeleine and Josephh M. Weber and R{\'e}jean Langlois and Ren{\'e} Ouellet and Johan E van Lier},
  journal={Photochemistry and photobiology},
  year={1999},
  volume={70 4},
  pages={
          512-23
        }
}
A brief summary of the mechanisms involved in photodynamic therapy (PDT) and the role of delivery vehicles for photosensitizer targeting is addressed. Phthalocyanines (Pc) have been coupled to adenovirus type 2 capsid proteins including the hexon, the penton base and the fiber to enhance their target selectivity. Adenovirus penton base proteins contain the arginine-glycine-aspartic acid peptidic sequence (RGD) motif known to bind with great affinity and high specificity to integrin receptors… CONTINUE READING

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Tumor Targeting in Cancer Therapy

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