Photodynamic therapy: the development of new photosensitisers.

@article{Wainwright2008PhotodynamicTT,
  title={Photodynamic therapy: the development of new photosensitisers.},
  author={Mark Wainwright},
  journal={Anti-cancer agents in medicinal chemistry},
  year={2008},
  volume={8 3},
  pages={
          280-91
        }
}
The first 20 years of anticancer photodynamic therapy (PDT) were based on the utility of the oligomeric mixture haematoporphyrin derivative (HpD) in various forms. More recently new derivatives have become available, both porphyrin-derived and employing new chromophores, for example from the phthalocyanine and phenothiazinium families. In addition, a major research effort has been rewarded with the clinical acceptance of the porphyrin precursor 5-aminolaevulinic acid (ALA). New photosensitisers… CONTINUE READING
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