Photodynamic inactivation of viruses using upconversion nanoparticles.

@article{Lim2012PhotodynamicIO,
  title={Photodynamic inactivation of viruses using upconversion nanoparticles.},
  author={Meng Earn Lim and Yen-Ling Lee and Yong Lin Zhang and Justin Jang-hann Chu},
  journal={Biomaterials},
  year={2012},
  volume={33 6},
  pages={1912-20}
}
Photodynamic therapy (PDT) is a promising treatment modality that utilizes light of an appropriate wavelength to excite photosensitive materials called photosensitizers, which upon excitation, generate reactive oxygen species (ROS) that are cytocidal and virucidal. However, problems such as hydrophobicity of photosensitizers and limited tissue penetration ability of the current light sources impeded its promotion as a mainstay in medical technology. Here, by using near-infrared (NIR)-to-visible… CONTINUE READING

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