Photodynamic effects of toluidine blue on human oral keratinocytes and fibroblasts and Streptococcus sanguis evaluated in vitro.

@article{Soukos1996PhotodynamicEO,
  title={Photodynamic effects of toluidine blue on human oral keratinocytes and fibroblasts and Streptococcus sanguis evaluated in vitro.},
  author={Nikolaos S. Soukos and Michael Wilson and Travis Burns and Paul M Speight},
  journal={Lasers in surgery and medicine},
  year={1996},
  volume={18 3},
  pages={253-9}
}
BACKGROUND AND OBJECTIVE Some oral bacteria are susceptible to killing by red light after their sensitization with toluidine blue O (TBO). The photochemotherapy of periodontal disease in vivo would require a therapeutic window where bacteria could be killed without adjacent normal tissue damage. STUDY DESIGN/MATERIALS AND METHODS The laser-induced effects of TBO on normal human gingival keratinocytes and fibroblasts have been studied in vitro. For the assessment of viability, the CellTiter… CONTINUE READING
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