Photodynamic diagnosis of breast tumours after oral application of aminolevulinic acid

@article{Ladner2001PhotodynamicDO,
  title={Photodynamic diagnosis of breast tumours after oral application of aminolevulinic acid},
  author={Daniela P. Ladner and Rolf A. Steiner and Juerg Allemann and Urs Haller and Heinrich Walt},
  journal={British Journal of Cancer},
  year={2001},
  volume={84},
  pages={33 - 37}
}
Photodynamic diagnosis is of increasing interest for diagnosis in oncology. It is based on a more intense incorporation of a fluorescent dye in tumours compared to normal tissue. As a feasibility study we investigated the effectiveness of oral application of 5-aminolevulinic acid for photodynamic diagnosis of human primary mammary tumours. The study included 16 patients with palpable breast tumours. Aminolevulinic acid was administered at a concentration of 40 mg kg−1 bodyweight 150–420 min… CONTINUE READING
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Pharmacokinetics studies on 5-aminolevulinic acid-induced protoprophyrin IX accumulation in tumors and normal tissue

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