Photodynamic Therapy of Skin Cancers: Sensitizers, Clinical Studies and Future Directives

@article{Rosa2000PhotodynamicTO,
  title={Photodynamic Therapy of Skin Cancers: Sensitizers, Clinical Studies and Future Directives},
  author={Fernanda Scarmato De Rosa and Maria Vit{\'o}ria Lopes Badra Bentley},
  journal={Pharmaceutical Research},
  year={2000},
  volume={17},
  pages={1447-1455}
}
Photodynamic therapy (PDT) is a new modality of skin cancer treatment. It involves the administration of photosensitizing drugs which, when localized in tumor tissue can produce its destruction by absorbing an adequate dose of light of an appropriate wavelength. A large number of photosensitizing agents have been tested in PDT experiments. Topical application of 5-aminolevulinic acid (5-ALA) followed by light irradiation is the most commonly used method. 5-ALA is a prodrug converted in situ via… CONTINUE READING